WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Protein digestion and absorption       ID:04974
C=81; O=8; E=0.30; R=26.96; rawP=6.96e-10; adjP=2.23e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000142173 NA COL6A2 collagen, type VI, alpha 2 1292 ENSG00000142173
2  ENSG00000204262 NA COL5A2 collagen, type V, alpha 2 1290 ENSG00000204262
3  ENSG00000108821 NA COL1A1 collagen, type I, alpha 1 1277 ENSG00000108821
4  ENSG00000130635 NA COL5A1 collagen, type V, alpha 1 1289 ENSG00000130635
5  ENSG00000142156 NA COL6A1 collagen, type VI, alpha 1 1291 ENSG00000142156
6  ENSG00000164692 NA COL1A2 collagen, type I, alpha 2 1278 ENSG00000164692
7  ENSG00000168542 NA COL3A1 collagen, type III, alpha 1 1281 ENSG00000168542
8  ENSG00000111799 NA COL12A1 collagen, type XII, alpha 1 1303 ENSG00000111799


Database:KEGG pathway       Name:ECM-receptor interaction       ID:04512
C=85; O=7; E=0.31; R=22.48; rawP=3.01e-08; adjP=4.82e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164692 NA COL1A2 collagen, type I, alpha 2 1278 ENSG00000164692
2  ENSG00000142173 NA COL6A2 collagen, type VI, alpha 2 1292 ENSG00000142173
3  ENSG00000204262 NA COL5A2 collagen, type V, alpha 2 1290 ENSG00000204262
4  ENSG00000108821 NA COL1A1 collagen, type I, alpha 1 1277 ENSG00000108821
5  ENSG00000168542 NA COL3A1 collagen, type III, alpha 1 1281 ENSG00000168542
6  ENSG00000130635 NA COL5A1 collagen, type V, alpha 1 1289 ENSG00000130635
7  ENSG00000142156 NA COL6A1 collagen, type VI, alpha 1 1291 ENSG00000142156


Database:KEGG pathway       Name:Focal adhesion       ID:04510
C=200; O=9; E=0.73; R=12.28; rawP=6.12e-08; adjP=6.53e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000162909 NA CAPN2 calpain 2, (m/II) large subunit 824 ENSG00000162909
2  ENSG00000142173 NA COL6A2 collagen, type VI, alpha 2 1292 ENSG00000142173
3  ENSG00000204262 NA COL5A2 collagen, type V, alpha 2 1290 ENSG00000204262
4  ENSG00000108821 NA COL1A1 collagen, type I, alpha 1 1277 ENSG00000108821
5  ENSG00000130635 NA COL5A1 collagen, type V, alpha 1 1289 ENSG00000130635
6  ENSG00000142156 NA COL6A1 collagen, type VI, alpha 1 1291 ENSG00000142156
7  ENSG00000164692 NA COL1A2 collagen, type I, alpha 2 1278 ENSG00000164692
8  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
9  ENSG00000168542 NA COL3A1 collagen, type III, alpha 1 1281 ENSG00000168542


Database:KEGG pathway       Name:Amoebiasis       ID:05146
C=106; O=7; E=0.39; R=18.03; rawP=1.39e-07; adjP=1.11e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164692 NA COL1A2 collagen, type I, alpha 2 1278 ENSG00000164692
2  ENSG00000204262 NA COL5A2 collagen, type V, alpha 2 1290 ENSG00000204262
3  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
4  ENSG00000108821 NA COL1A1 collagen, type I, alpha 1 1277 ENSG00000108821
5  ENSG00000168542 NA COL3A1 collagen, type III, alpha 1 1281 ENSG00000168542
6  ENSG00000156049 NA GNA14 guanine nucleotide binding protein (G protein), alpha 14 9630 ENSG00000156049
7  ENSG00000130635 NA COL5A1 collagen, type V, alpha 1 1289 ENSG00000130635


Database:KEGG pathway       Name:Fc gamma R-mediated phagocytosis       ID:04666
C=94; O=4; E=0.34; R=11.62; rawP=0.0004; adjP=0.0026
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116711 NA PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 5321 ENSG00000116711
2  ENSG00000155130 NA MARCKS myristoylated alanine-rich protein kinase C substrate 4082 ENSG00000155130
3  ENSG00000145555 NA MYO10 myosin X 4651 ENSG00000145555
4  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851


Database:KEGG pathway       Name:Sulfur metabolism       ID:00920
C=13; O=2; E=0.05; R=41.99; rawP=0.0010; adjP=0.0053
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000136213 NA CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 55501 ENSG00000136213
2  ENSG00000138801 NA PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 9061 ENSG00000138801


Database:KEGG pathway       Name:Pancreatic secretion       ID:04972
C=101; O=3; E=0.37; R=8.11; rawP=0.0062; adjP=0.0220
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116711 NA PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 5321 ENSG00000116711
2  ENSG00000109743 NA BST1 bone marrow stromal cell antigen 1 683 ENSG00000109743
3  ENSG00000121281 NA ADCY7 adenylate cyclase 7 113 ENSG00000121281


Database:KEGG pathway       Name:Chemokine signaling pathway       ID:04062
C=189; O=4; E=0.69; R=5.78; rawP=0.0053; adjP=0.0220
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000186469 NA GNG2 guanine nucleotide binding protein (G protein), gamma 2 54331 ENSG00000186469
2  ENSG00000156299 NA TIAM1 T-cell lymphoma invasion and metastasis 1 7074 ENSG00000156299
3  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
4  ENSG00000121281 NA ADCY7 adenylate cyclase 7 113 ENSG00000121281


Database:KEGG pathway       Name:GnRH signaling pathway       ID:04912
C=101; O=3; E=0.37; R=8.11; rawP=0.0062; adjP=0.0220
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116711 NA PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 5321 ENSG00000116711
2  ENSG00000095015 NA MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 4214 ENSG00000095015
3  ENSG00000121281 NA ADCY7 adenylate cyclase 7 113 ENSG00000121281


Database:KEGG pathway       Name:Regulation of actin cytoskeleton       ID:04810
C=213; O=4; E=0.78; R=5.13; rawP=0.0080; adjP=0.0256
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000068793 NA CYFIP1 cytoplasmic FMR1 interacting protein 1 23191 ENSG00000068793
2  ENSG00000156299 NA TIAM1 T-cell lymphoma invasion and metastasis 1 7074 ENSG00000156299
3  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
4  ENSG00000145703 NA IQGAP2 IQ motif containing GTPase activating protein 2 10788 ENSG00000145703




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).